منابع مشابه
Inflammatory Disequilibrium in Stroke.
Over the past several decades, there have been substantial advances in our knowledge of the pathophysiology of stroke. Understanding the benefits of timely reperfusion has led to the development of thrombolytic therapy as the cornerstone of current management of ischemic stroke, but there remains much to be learned about mechanisms of neuronal ischemic and reperfusion injury and associated infl...
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Basic and clinical research provides evidence that inflammatory mechanisms play a central role in the pathogenesis and progression of atherosclerosis, plaque rupture, thrombosis, and stroke. Inflammatory biomarkers such as high-sensitivity C-reactive protein have been identified as predictors of first stroke and prognosis after stroke. The value of high-sensitivity C-reactive protein and other ...
متن کاملCorrelation Between Cannabidiol-Induced Reduction of Infarct Volume and Inflammatory Factors Expression in Ischemic Stroke Model
Introduction: Recent studies demonstrated that cannabidiol had neuroprotective property. Thereis some evidence about effective role of cannabidiol in reducing ischemic damages. It has been reported that infarct size is influenced by various factors after MCAO, including inflammatory factors. The aim of the present study was to evaluate the effect of cannabidiol on infarction volume and correlat...
متن کاملInflammatory Biomarkers in Childhood Arterial Ischemic Stroke
Although childhood arterial ischemic stroke (AIS) is a heterogeneous disorder, most cases fall into 1 of 3 broad pathogenic categories: arteriopathic, cardioembolic, and idiopathic. The presence of an arteriopathy (cervical or cerebral) confers an increased risk of recurrent AIS. In the prospective, multicenter VIPS study (Vascular Effects of Infection in Pediatric Stroke), children with arteri...
متن کاملInflammatory cytokines in experimental and human stroke.
Inflammation is a hallmark of stroke pathology. The cytokines, tumor necrosis factor (TNF), interleukin (IL)-1, and IL-6, modulate tissue injury in experimental stroke and are therefore potential targets in future stroke therapy. The effect of these cytokines on infarct evolution depends on their availability in the ischemic penumbra in the early phase after stroke onset, corresponding to the t...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 2016
ISSN: 0009-7330,1524-4571
DOI: 10.1161/circresaha.116.308022